List of Antibiotics

 a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v, w, x-y, z, other

(-)-6-Aminopenacillaric Acid; Interferes with cell wall synthesis

(+)-Usnic Acid; Inhibits an enzyme

1,10-Phenathroline hydrochloride monohydrate puriss; Inhibits an enzyme

10-Deacetylbaccatin III; Interferes with DNA Synthesis

1-Deoxymannojirimycin HCL; Inhibits an enzyme

2-Heptyl-4-hyroxyquinolone N-oxide; Inhibits an enzyme

2-Mercaptopyridine N-oxide sodium salt; Interferes with cell membrane permeability (ionophores)

4-Bromocalcimycin A23187; Interferes with cell membrane permeability (ionophores)

5-Azacytidine ; Interferes with DNA Synthesis

6-Diazo-5-oxo-L-norleucine; Inhibits an enzyme

7-Aminoactinomycin D; Interferes with DNA Synthesis

7-Aminodesacetoxycephalosporanic Acid; Interferes with cell wall synthesis

8-Quinolinol; Inhibits an enzyme

8-Quinolinol; Interferes with DNA Synthesis

9-Dihydro-13-acetylbaccatin III; Interferes with DNA Synthesis

A

Aclarubicin; Interferes with DNA Synthesis

Actinomycin D; Interferes with DNA Synthesis

Actinomycin; Interferes with DNA Synthesis

Alamethicin Trichoderma viride; Interferes with cell membrane permeability (ionophores)

Amikacin  Interferes with Protein Synthesis

Amikacin (IV) Group: Aminoglycosides

Amoxicillin (PO) Group: Penicillins

Amoxicillin/Clavulanate (PO) Group: Penicillins

Amoxicillin; Interferes with cell wall synthesis

Amphotericin B (IV) Group: Polyene Antifungals

Amphotericin B; Interferes with cell membrane permeability (ionophores)

Ampicillin (IV/PO) Group: Penicillins

Ampicillin/Sulbactam (IV) Group: Penicillins

Ampicillin; Interferes with cell wall synthesis

Anisomycin Interferes with Protein Synthesis

Antimycin; Inhibits an enzyme

Antipain; Inhibits an enzyme

Aphidicolin Nigrospora; Interferes with DNA Synthesis

Apramycin Interferes with Protein Synthesis

Ascomycin; Inhibits an enzyme

Azaserine; Inhibits an enzyme

Aziocillin; Interferes with cell wall synthesis

Azithromycin (IV/PO) Group: Macrolides/Ketolides

Azithromycin Interferes with Protein Synthesis

Azole Antifungals

Aztreonam (IV) Group: Monobactams

B

Bacampicillin (PO) Group: Penicillins

Bacitracin; Interferes with cell wall synthesis

Bafilomycin; Inhibits an enzyme

Bafilomycin; Interferes with DNA Synthesis

Blasticidine Interferes with Protein Synthesis

Bleomycin sulfate; Interferes with DNA Synthesis

Brefeldin A Interferes with Protein Synthesis

Butirosin Interferes with Protein Synthesis

C

Calcimycin A23187; Interferes with cell membrane permeability (ionophores)

Camptothecin; Inhibits an enzyme

Camptothecin; Interferes with DNA Synthesis

Capreomycin; Interferes with DNA Synthesis

Carbenicillin (PO) Group: Penicillins

Carbenicillin; Interferes with cell wall synthesis

Caspofungin (IV) Group: Echinocandin (Glucan Synthesis Inhibitor) Antifungal

Cefaclor (PO) Group: 2^nd Generation Cephalosporins

Cefaclor; Interferes with cell wall synthesis

Cefadroxil (PO) Group: 1^st Generation Cephalosporins

Cefamandole (IV) Group: 2^nd Generation Cephalosporins

Cefamandole; Interferes with cell wall synthesis

Cefasulodin; Interferes with cell wall synthesis

Cefazolin; Interferes with cell wall synthesis

Cefdinir (PO) Group: 3^rd Generation Cephalosporins

Cefditoren (PO) Group: 3^rd Generation Cephalosporins

Cefeprime (IV) Group: 4^th Generation Cephalosporins

Cefixime (PO) Group: 3^rd Generation Cephalosporins

Cefmetazole; Interferes with cell wall synthesis

Cefonicid Group: 2^nd Generation Cephalosporins

Cefoperazone (IV) Group: 3^rd Generation Cephalosporins

Cefoperazone; Interferes with cell wall synthesis

Cefotaxime (IV) Group: 3^rd Generation Cephalosporins

Cefotaxime; Interferes with cell wall synthesis

Cefotetan (IV) Group: 2^nd Generation Cephalosporins

Cefoxitin (IV) Group: 2^nd Generation Cephalosporins

Cefpodoxime (PO) Group: 3^rd Generation Cephalosporins

Cefprozil (PO) Group: 2^nd Generation Cephalosporins

Ceftazidime (IV) Group: 3^rd Generation Cephalosporins

Ceftibuten (PO) Group: 3^rd Generation Cephalosporins

Ceftizoxime (IV) Group: 3^rd Generation Cephalosporins

Ceftriaxone (IV) Group: 3^rd Generation Cephalosporins

Cefuroxime (IV/PO) Group: 2^nd Generation Cephalosporins

Cephalexin (PO) Group: 1^st Generation Cephalosporins

Cephalexin; Interferes with cell wall synthesis

Cephalosporin; Interferes with cell wall synthesis

Cephalothin Group: 1^st Generation Cephalosporins

Cephalothin; Interferes with cell wall synthesis

Cephapirin Group: 1^st Generation Cephalosporins

Cephapirin; Interferes with cell wall synthesis

Cephradine Group: 1^st Generation Cephalosporins

Cephradine; Interferes with cell wall synthesis

Cerulenin; Inhibits an enzyme

Chloramphenicol (IV/PO) Group: Chloramphenicol

Chloramphenicol Interferes with Protein Synthesis

Chlorhexidine; Interferes with cell membrane permeability (ionophores)

Chloroquine; Inhibits an enzyme

Chlortetracycline hydrochloride Interferes with Protein Synthesis

Chromomycin A3; Interferes with DNA Synthesis

Ciclopirox Group: Antifungal

Cinoxacin; Inhibits an enzyme

Cinoxacin; Interferes with DNA Synthesis

Ciprofloxacin (IV/PO) Group: Fluoroquinolones

Ciprofloxacin; Inhibits an enzyme

Ciprofloxacin; Interferes with DNA Synthesis

Cis-Diammineplatinum; Interferes with DNA Synthesis

Clarithromycin (PO) Group: Macrolides/Ketolides

Clindamycin (IV/PO) Group: Lincosamides

Clindamycin Interferes with Protein Synthesis

Clotrimazole Group: Azole Antifungals

Clotrimazole Interferes with Protein Synthesis

Clotrimazole; Interferes with cell membrane permeability (ionophores)

Cloxacillin Group: Penicillins

Cloxacillin; Interferes with cell wall synthesis

Colistin; Interferes with cell membrane permeability (ionophores)

Concanamycin; Inhibits an enzyme

Cordycepin; Interferes with DNA Synthesis

Corycepin BioChemika; Inhibits an enzyme

Coumermycin A1; Interferes with DNA Synthesis

Coumerycin; Inhibits an enzyme

Cycloheximide Interferes with Protein Synthesis

Cyclosporine; Inhibits an enzyme

Cytochalacin ; Interferes with DNA Synthesis

D

D-(-)-penicillamine HCL; Interferes with cell wall synthesis

Dacarbazine ; Interferes with DNA Synthesis

Daunoribicin HCL; Interferes with DNA Synthesis

D-Cycloserine; Interferes with cell wall synthesis

Defaxolin (IV) Group: 1^st Generation Cephalosporins

Deftraxone; Interferes with cell wall synthesis

Demeclocycline Group: Tetracyclines

Demeclocycline HCL Interferes with Protein Synthesis

Dibekacin  Interferes with Protein Synthesis

Dicloxacillin Group: Penicillins

Dicloxacillin; Interferes with cell wall synthesis

Dihydrostreptomycin Interferes with Protein Synthesis

Dirithromycin Group: Macrolides/Ketolides

Distamycin A HCL; Interferes with DNA Synthesis

DL-Penicillamine; Interferes with cell membrane permeability (ionophores)

Doxorubicin HCL; Interferes with DNA Synthesis

Doxycycline (IV/PO) Group: Tetracyclines

Doxycycline Interferes with Protein Synthesis

D-Penicillamine; Interferes with cell wall synthesis

Duramycin Interferes with Protein Synthesis

E

Echinomycin; Interferes with DNA Synthesis

Econazole Nitrate Salt; Interferes with cell membrane permeability (ionophores)

Econazole nitrate; Interferes with cell wall synthesis

Econazole; Inhibits an enzyme

Emetine Interferes with Protein Synthesis

Enrofloxacin; Inhibits an enzyme

Enrofloxacin; Interferes with DNA Synthesis

Ertapenem (IV/IM) Group: Carbapenems

Erythromycin (IV/PO) Group: Macrolides/Ketolides

Erythromycin Interferes with Protein Synthesis

Erythromycin Interferes with Protein Synthesis

Ethambutol dihydrochloride; Interferes with cell wall synthesis

Etoposide; Inhibits an enzyme

Etoposide; Inhibits an enzyme

Etoposide; Interferes with DNA Synthesis

F

Filipin Complex; Interferes with cell membrane permeability (ionophores)

Fluconaxole (IV/PO) Azole Antifungals

Flucytosine (PO) Group: Antifungal

Flumequine; Inhibits an enzyme

Flumequine; Interferes with DNA Synthesis

Formycin A; Inhibits an enzyme

Formycin A; Interferes with DNA Synthesis

Formycin; Interferes with DNA Synthesis

Fulfaguanidine; Inhibits an enzyme

Fumagillin; Interferes with DNA Synthesis

Furaxolidone; Inhibits an enzyme

Fusaric acid; Inhibits an enzyme

Fusidic acid Interferes with Protein Synthesis

G

G418 Disulfate Salt Interferes with Protein Synthesis

Ganciclovir; Interferes with DNA Synthesis

Gatifloxacin (IV/PO) Group: Fluoroquinolones

Geldanamycin; Inhibits an enzyme

Gemifloxacin (PO) Group: Fluoroquinolones

Gentamycin (IV) Group: Aminoglycosides

Gentamycin Interferes with Protein Synthesis

Girseofulvin (PO) Group: Antifungal

Gliotoxin; Inhibits an enzyme

Gliotoxin; Interferes with cell membrane permeability (ionophores)

Gliotoxin; Interferes with DNA Synthesis

Gramicidin; Inhibits an enzyme

Gramicidin; Interferes with cell membrane permeability (ionophores)

Grepafloxacin (PO) Group: Fluoroquinolones

H

Helvolic Acid Interferes with Protein Synthesis

Herbimycin A; Inhibits an enzyme

Hydrocortisone 21-acetate (Vetranal) ; Interferes with cell membrane permeability (ionophores)

Hygromycin B Streptomyces Interferes with Protein Synthesis

I

Imipenem (IV) Group: Carbapenems

Indomethacin; Inhibits an enzyme

Ionomycin; Interferes with cell membrane permeability (ionophores)

Irgasan; Inhibits an enzyme

Itraconazole (IV/PO) Azole Antifungals

J

Josamycin  Interferes with Protein Synthesis

K

Kanamycin B Interferes with Protein Synthesis

Kanamycin Group: Aminoglycosides

Kanamycin Interferes with Protein Synthesis

Ketoconaxole (PO) Azole Antifungals

Kirromycin Interferes with Protein Synthesis

L

L(+)-Lactic Acid; Inhibits an enzyme

L(+)-Lactic Acid; Interferes with DNA Synthesis

Lasalocid; Interferes with cell membrane permeability (ionophores)

Levofloxacin (IV/PO) Group: Fluoroquinolones

Lincomycin Interferes with Protein Synthesis

Linezolid (IV/PO) Group: Oxazolidinones

Lomefloxacin Group: Fluoroquinolones

Lomefloxacin HCL; Interferes with DNA Synthesis

Lomefloxacin; Inhibits an enzyme

Lonomycin; Interferes with cell membrane permeability (ionophores)

Loracarbef (PO) Group: 2^nd Generation Cephalosporins

Lysostaphin; Interferes with cell wall synthesis

M

Meclocydine Interferes with Protein Synthesis

Mepartricin Interferes with Protein Synthesis

Mefoxin is one of several broad spectrum cephalosporin antibiotic substances obtained from fungi and related to penicillin (trade names Mefoxin); addition of side chains has produced semisynthetic antibiotics with greater antibacterial activity.

Meropenem (IV) Group: Carbapenems

Methicillin Group: Penicillins

Metronidazole (IV/PO) Group: Nitroimidazoles

Metronidazole; Interferes with DNA Synthesis

Mevasatin; Inhibits an enzyme

Mezlocillin (IV) Group: Penicillins

Micafungin Group: Echinocandin (Glucan Synthesis Inhibitor) Antifungal

Miconazole Group: Azole Antifungals

Miconazole; Inhibits an enzyme

Midecamycin Interferes with Protein Synthesis

Minocycline (IV/PO) Group: Tetracyclines

Minocycline HCL Interferes with Protein Synthesis

Mirthrmitomycin C; Interferes with DNA Synthesis

Mithramycin; Interferes with DNA Synthesis

Mitomycin C; Interferes with DNA Synthesis

Monensin; Interferes with cell membrane permeability (ionophores)

Moxalactam; Interferes with cell wall synthesis

Moxifloxacin (IV/PO) Group: Fluoroquinolones

Mycophenolic Acid; Inhibits an enzyme

Myxothiazol; Inhibits an enzyme

N

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide HCL; Inhibits an enzyme

N-(6-Aminohyxy)-5-chloro-1-napthalenesulfonamide HCL; Interferes with cell membrane permeability (ionophores)

Nafcillin (IV) Group: Penicillins

Nafcillin; Interferes with cell wall synthesis

Nalidixic Acid; Inhibits an enzyme

Nalidixic Acid; Inhibits an enzyme

Nalidixic Acid; Interferes with DNA Synthesis

Narasin; Interferes with cell membrane permeability (ionophores)

Neomycin Group: Aminoglycosides

Neomycin Interferes with Protein Synthesis

Neomycin trisulfate Interferes with Protein Synthesis

Netilmicin Group: Aminoglycosides

Netilmicin Interferes with Protein Synthesis

Netropsin dihydrochloride; Interferes with DNA Synthesis

Netropsin; Inhibits an enzyme

Niclosamide; Inhibits an enzyme

Nigericin; Interferes with cell membrane permeability (ionophores)

Nikkomycin; Inhibits an enzyme

Nikkomycin; Interferes with cell wall synthesis

Nisin; Interferes with cell membrane permeability (ionophores)

Nitrofurantoin Interferes with Protein Synthesis

Nitrofurantoin; Interferes with cell wall synthesis

Nitrofurantoin; Interferes with DNA Synthesis

N-Methyl-1-deoxynojirimycin; Inhibits an enzyme

Nogalamycin; Inhibits an enzyme

Nogalamycin; Interferes with DNA Synthesis

Nonactin; Inhibits an enzyme

Nonactin; Interferes with cell membrane permeability (ionophores)

Nonactin; Interferes with DNA Synthesis

Norfloxacin Group: Fluoroquinolones

Nourseothricin Sulfate Interferes with Protein Synthesis

Novobiocin; Inhibits an enzyme

Novobiocin; Interferes with DNA Synthesis

Nystatin Group: Polyene Antifungals

Nystatin; Interferes with cell membrane permeability (ionophores)

O

Ofloxacin (IV/PO) Group: Fluoroquinolones

Ofloxacin; Inhibits an enzyme

Ofloxacin; Interferes with DNA Synthesis

Oleandomycin  Interferes with Protein Synthesis

Oleandomycin; Inhibits an enzyme

Oligomycin; Inhibits an enzyme

Oxacillin (IV) Group: Penicillins

Oxacilllin; Interferes with cell wall synthesis

Oxolinic Acid; Inhibits an enzyme

Oxolinic acid; Interferes with DNA Synthesis

Oxytetracycline Interferes with Protein Synthesis

P

Paclitaxel; Interferes with DNA Synthesis

Paracelsin Trichoderma; Modifies membranes

Paromomycin Group: Aminoglycosides

Paromomycin Interferes with Protein Synthesis

Penicilic Acid; Interferes with cell wall synthesis

Penicillin G (IV) Group: Penicillins

Penicillin G; Interferes with cell wall synthesis

Penicillin V (PO) Group: Penicillins

Phenazine; Interferes with cell membrane permeability (ionophores)

Phenethicillin; Interferes with cell wall synthesis

Phenoxymethylpenicllinic Acid; Interferes with cell wall synthesis

Phenzine methosulfate; Interferes with DNA Synthesis

Phleomycin; Interferes with DNA Synthesis

Phosphomycin; Interferes with cell wall synthesis

Piericidin; Inhibits an enzyme

Pimaricin; Interferes with cell membrane permeability (ionophores)

Pipemidic Acid; Inhibits an enzyme

Pipemidic Acid; Interferes with cell wall synthesis

Pipemidic Acid; Interferes with DNA Synthesis

Piperacillin (IV) Group: Penicillins

Piperacillin/Tazobactam (IV) Group: Penicillins

Piperacillin; Interferes with cell wall synthesis

Polymixin; Interferes with cell membrane permeability (ionophores)

Polymyxin B; Interferes with cell membrane permeability (ionophores)

Praziquantel; Interferes with cell membrane permeability (ionophores)

Puromycin  Interferes with Protein Synthesis

Puromycin aminonucleoside Interferes with Protein Synthesis

Q

Quinupristin/Dalfopristin (IV) Group: Streptogramins

R

Radicicol; Inhibits an enzyme

Rapamycin Interferes with Protein Synthesis

Rapamycin; Inhibits an enzyme

Rebeccamycin; Inhibits an enzyme

Rebeccamycin; Interferes with DNA Synthesis

Ribostamycin Interferes with Protein Synthesis

Rifampicin Interferes with Protein Synthesis

Rifamycin Interferes with Protein Synthesis

Ristomycin; Interferes with cell wall synthesis

Rosamicin Interferes with Protein Synthesis

S

Salinomycin; Interferes with cell membrane permeability (ionophores)

Sinefungin; Inhibits an enzyme

Sinefungin; Interferes with DNA Synthesis

Sisomicin Interferes with Protein Synthesis

Sparfloxacin (PO) Group: Fluoroquinolones

Specrinomycin Interferes with Protein Synthesis

Spiramycin Interferes with Protein Synthesis

Staurosporine; Inhibits an enzyme

Stigmatellin; Inhibits an enzyme

Streptomycin (IM) Group: Aminoglycosides

Streptomycin Interferes with Protein Synthesis

Streptonigrin; Interferes with DNA Synthesis

Streptozocin; Interferes with DNA Synthesis

Succinylsulfathiazole; Inhibits an enzyme

Succinylsulfathiazole; Interferes with DNA Synthesis

Sulfadiazine; Inhibits an enzyme

Sulfadiazine; Interferes with DNA Synthesis

Sulfadimethoxine; Inhibits an enzyme

Sulfamethazine; Inhibits an enzyme

Sulfamethazine; Interferes with DNA Synthesis

Sulfamethoxazole/Trimethoprim (IVPO) Group: Sulfonamide/Folate Antagonist

Sulfamonomethoxine; Inhibits an enzyme

Sulfamonomethoxine; Interferes with DNA Synthesis

Sulfanilamide; Inhibits an enzyme

Sulfanilamide; Interferes with DNA Synthesis

Sulfaquanidine; Interferes with DNA Synthesis

Sulfaquinoxaline; Inhibits an enzyme

Sulfaquinoxaline; Interferes with DNA Synthesis

Sulfasalazine; Inhibits an enzyme

Sulfasalazine; Interferes with DNA Synthesis

Sulfathiazole; Interferes with enzyme or DNA Synthesis

T

Telithromycin Group: Macrolides/Ketolides

Temephos PESTANAL Interferes with Protein Synthesis

Terbinafine (PO) Group: Antifungal

Tetracycline (PO) Group: Tetracyclines

Tetracycline Interferes with Protein Synthesis

Thiamphenicol Interferes with Protein Synthesis

Ticarcillin (IV) Group: Penicillins

Ticarcillin/Clavulanate (IV) Group: Penicillins

Tobramycin (IV) Group: Aminoglycosides

Tobramycin Interferes with Protein Synthesis

Triascin C; Inhibits an enzyme

Trimethoprim; Inhibits an enzyme

Trimethoprim; Interferes with DNA Synthesis

Trovafloxacin (IV/PO) Group: Fluoroquinolones

Tubercidin; Interferes with DNA Synthesis

Tubercidin; Interferes with DNA Synthesis

Tunicamycin  Interferes with Protein Synthesis

Tylosin Interferes with Protein Synthesis

U V

Valinomycin; Interferes with cell membrane permeability (ionophores)

Vancomycin (IV) Group: Glycopeptides

Vancomycin HCL; Interferes with cell wall synthesis

Vincomycin A; Inhibits an enzyme

Viomycin Interferes with Protein Synthesis

Virginiamycin Interferes with Protein Synthesis

Voriconazole (IV/PO) Azole Antifungals

W, X, Y, Z

Other

y-Tectorigenin; Inhibits an enzyme

References and Links:

http://www.sigmaaldrich.com/Area_of_Interest/Biochemicals/Antibiotic_Explorer/Mechanism_of_Action.html

http://www.mi-marr.org/documents/CommonAntibiotics_000.pdf