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Drugs That Can Cause

Urinary Stones and Crystals

  

Acyclovir: A drug used in the treatment of Herpes and other viruses.

Acyclovir crystals in urine pic 

Picture Reference: http://www.ndt-educational.org/fogazzislidepart3.asp

 

Aminophylline : An asthma bronchodilator drug.

 

 Stones caused by aminophylline

 Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met  

 

Amoxicillin a common antibiotic used for gobs of stuff! Here’s an Amoxicillin crystal in urine:

Amoxicillin Crystals in Urine

Picture Reference: http://www.ndt-educational.org/fogazzislidepart3.asp

 

Antacids: Taking too many antacids (like Tums) increases the calcium output of the kidneys and concentrates it in the urine predisposing to crystal and stone formation.  Antacids reduce stomach acidity temporarily which may result in impaired ability to digest and absorb certain nutrients such as iron and B Vitamins. Also, healthy stomach acid kills ingested bacteria, viruses and parasites so the addition of antacids may increase the body’s vulnerability to infection to these organisms. Calcium supplements may also bind up certain drugs like ketoconazole which is used as an antifungal agent so that they do not work as effectively.

 

Ciprofloxacin : Ciprofloxacin extended-release (long-acting) tablets are used only to treat certain types of urinary tract infections. Ciprofloxacin is in a class of antibiotics called fluoroquinolones. It works by killing bacteria.

Photo of stone caused by ciprofloxacin

Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met  

 

Guaifenasin : Guaifenasin thins the mucus in the air passages and makes it easier to cough up the mucus and clear the airways, allowing you to breathe more easily. It relieves the coughs of colds, bronchitis, and other lung infections. It is in some cough remedies.

 

 Photograph of Guafenasin bladder stones 

Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met   

 

Indinavir: A drug used in the treatment of HIV.

 

Indiavir crystals in urine slide stone caused by indiavir 

Picture Reference: http://www.ndt-educational.org/fogazzislidepart3.asp

Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met  

 

Iothalamate: A renal dialysis drug.

 

L-Methyl glucamine (Meglamine): A drug used in radiography studies (Gastrographin), in the treatment of diabetes, in anti-aging creams (MEG-21 and Supplamine) and as an antiprotozoal medication used in the treatment of leishmaniasis. Methylglucamine, also known as meglumine, is an amino sugar which is chemically related to the naturally occurring sugar, sorbitol.

 

methylglucamine crystals 

Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met  

 

Oxypurinol: A drug used in the treatment of gout. Hmmm.

 

oxypurinol kidney stones 

Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met  

 

Phenazopyridine: Relieves urinary tract pain, burning, irritation, and discomfort, as well as urgent and frequent urination caused by urinary tract infections, surgery, injury, or examination procedures. Now isn’t that weird. A drug used to treat a symptom of urinary tract infection causing yet more problems!)

 

 phenazopyridine stones pic 

Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met   

 

Phenytoin: Epilepsy drug used also for treating Hirsutism (hairy faces in women) and Poly Cystic Ovarian Disease.

 

Primidone: An anti-seizure medication

 

Pyridoxalate:

 

Sulfa drugs: Antibiotic used for bladder infections. Slide with crystal:

 

sulfa drug crystals in urineSulfadiazine crystals picture 

Picture Reference: http://www.ndt-educational.org/fogazzislidepart3.asp

 

Sulfamethoxazole metabolite: Used in the treatment of bacterial infections—an antibiotic.

sulfamethoxazole stones 

Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met  

 

Thyroid Hormones: Can increase the amount of calcium excreted into the system and can occasionally cause calcium-based stones.

 

Triamterene and Metabolites (A potassium sparing diuretic used in the treatment of fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney condition called nephrotic syndrome.

 

drug induced triampterine stones

Picture Reference: http://www.herringlab.com/photos/Urinary/Drug&Met  

 

Vitamin C (Causes monohydrate calcium oxalate crystals) I suspect it is actually Ascorbic Acid which is only one molecule of Vitamin C that they are talking about here.

 

Other Helpful Links and Pages on this Site:

 

Alternative Treatments for Stones

Drugs Causing Stones & Crystals

Gout

High Oxalate Food List

Hydrangea Root

Kidney, Bladder & Gall Stones

Medical Treatment of Stones

Species & Breed Predilection to Stones

Urinalysis-What is it? What do they see?

 

Links and References:

 

Drug Interaction Checker

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